… response, we examined the antinociceptive activities of various fatty acid ethanolamide
analogs of palmitylethanolamide. Oleylethanolamide (shorthand fatty acid designation, 18:1Δ 9 …

… fatty acid amide hydrolase … factor, activated by various endogenous fatty acid derivatives,
including PEA and … Consistently, the antinociceptive activity of PEA was partially reduced in two …

… another fatty acid amide, anandamide (arachidonoylethanolamide), is an endogenous agonist
for … , but also identify new potential targets for analgesic and anti-inflammatory medicines. …

… hydrolysis to palmitic acid and ethanolamine. Apart from fatty acid amide hydrolase (FAAH), …
and effective NAAA inhibitors able to increase the endogenous levels of PEA. EPT4900 was …

… Cannabinoids produce antinociception in animal models of … (2-AG) are endogenous ligands
for the cannabinoid receptors… study is the first to document antinociceptive effects of the MGL …

… mast cell activity has led to the application of this fatty acid amide in … A wide range of analgesic
medications are currently … the view of PEA as an endogenous anti-inflammatory agent. In …

… Oleoylethanolamide (OEA) is a natural fatty acid amide that mainly … The analgesic activity
of OEA was measured against … and structurally related to the endogenous cannabinoid …

… hypothesis that PEA is an endogenous mediator whose levels are … to exert a local anti-inflammatory
and analgesic action. … PMSF is an inhibitor of fatty acid amide hydrolase (FAAH), and …

… of long-chain fatty acids degraded by fatty acid amide hydrolase (… , anti-oedema and analgesic
properties in a wide range of … -inflammatory (40, 41) and analgesic activity (42–44), in part …

… Also, primary fatty acid amides, including the amide of oleic acid, which acts as a sleep-…
of the cannabinoid receptor-inactive N -acylethanolamines and primary fatty acid amides. …